ADFC1209-12P Dissolution Sampling System

ADFC1209-12P dissolution sampling system performance indicators, in line with the 2020 edition of the Chinese Pharmacopoeia requirements. In order to ensure the basic functions of the original dissolution instrument, the instrument has added the functions of automatic drug delivery; single-cup temperature measurement; homogeneous temperature replenishment; automatic sampling, etc. The control mode adopted makes the whole machine run stably and reliably, which is a high-end instrument of dissolution series products.

  Performance features:

◎ 12-channel temperature monitoring inside the cup.

◎ Automatic lifting of sampling needle and automatic positioning of sampling height.

◎ Can be connected to the P series autosampler, remote control operation, a screen to complete all operations.

◎ Head with the overall sealing cup cover, can effectively prevent the evaporation of dissolved media head electric lift (12 paddles / baskets synchronized lift), each paddle / basket rod can be manually disassembled individually. Paddle, basket rod automatic height setting.

◎ Adopt 7-inch large LCD touch screen, easy to understand the operation.

◎ The instrument is connected to the server through the network, connected to the LIMS system, you can choose to log in to the system in both offline and network applications.

◎ The instrument system is equipped with access control rights management function, audit trail, lock screen, data backup, etc. in line with the 2020 edition of the Pharmacopoeia of the People's Republic of China and the provisions of the national industry standards and requirements related to data integrity.

◎ There are three levels of user level management rights, with audit trail function.

◎ With low temperature alarm (<3℃), high temperature alarm (>47℃) and water shortage protection function.

◎ Specially designed automatic dosage device to realize synchronous dosage in paddle method experiment.

◎ Optional micro-printer to print the experimental records (including time, temperature, speed and other test data).

◎ Optional full-data high-precision dissolution cups, each dissolution cup with a certified report of 3D scanning, high-precision dissolution cups with more accurate internal dimensions and spherical radius structure to ensure the accuracy and repeatability of the dissolution experiment.

  Skill indicators:

◎ Stirring paddle and rotating basket specifications in accordance with the Pharmacopoeia regulations

◎ Stirring paddle swinging amplitude: ≤0.5mm

◎ Swinging amplitude of rotary basket: ≤1.0mm

◎ Deviation of the rotating rod from the dissolving cup shaft: ≤1.0mm

Speed range: (5-250) rpm

Speed resolution: 1 rpm

Speed stabilization error: ≤±1%.

Temperature range: 5.0 (room temperature)-45.0°C

Temperature resolution: 0.1℃ ◎ Temperature control error: ≤±1% ◎ Temperature resolution: 0.1

Temperature control error: ≤±0.2℃ ◎ Operating noise: ＜60%.

◎ Working noise: <60db

◎ Environmental conditions: ambient temperature 5-37 ℃, relative humidity ≤ 80

◎ Safety performance: in line with national industry standards, with self-test and automatic protection function

◎ Power supply: 220V, 50Hz, 10A

◎ Maximum sampling times: unlimited (16 times per batch), manual replacement of the sample disk

◎ Sample holder: 12X16 hole position

◎ Sampling volume: 0.1-10mL; 20mL (double row) 30mL (three row);

◎ Sampling interval: ≥ 2min  

◎ Sampling consistency: inter-channel RSD ≤ 1%;

◎ Sampling repeatability: RSD≤1%;

◎ Communication interface: RS232, RS485, network;

◎ In-line filter: 0.45um, 0.8um luer connector type filter;

◎ Liquid flow rate: programmable, ≤25mL/min;

◎ Method storage: flexible programming to adapt to various situations, within 20 times dilution.